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This historical trajectory strongly suggests that GLP-1 should not be viewed as an isolated success, but rather as a prototype for a much larger class of peptidereceptor systems whose translational potential remains unrealized

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[DOI] [PMC free article] [PubMed] [Google Scholar] 40.Kelly A.S., Auerbach P., Barrientos-Perez M., Gies I., Hale P.M., Marcus C., Mastrandrea L.D., Prabhu N., Arslanian S., NN8022-4180 Trial Investigators A Randomized, Controlled Trial of Liraglutide for Adolescents with Obesity