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Classically, it should not be used as a screening method for diagnosing asymptomatic patients and its use in patients with signs or symptoms is a subject of debate, given that ammonia is not specific for diagnosing HE

Feb 1 2018;144(2):115-126

For individuals who tolerate the medication well, staying on it longer term can play an important role in maintaining weight loss and supporting ongoing metabolic health, Ali said.

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