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The fit for GLP-1 users is in metabolic-and-appetite biology rather than direct constipation relief

The predominant side effects include: Gastrointestinal symptoms : nausea, vomiting, diarrhoea, constipation, and abdominal pain (affecting 10-50% of patients depending on the specific product and dose, particularly during dose escalation) Injection site reactions : redness, itching, or discomfort at the subcutaneous injection site Hypoglycaemia : particularly when combined with insulin or sulphonylureas Decreased appetite : an intended therapeutic effect that contributes to weight loss However, some patients do report changes in urinary frequency or patterns

Instead, if MB is used in a pain management context (e.g., oral rinse for mucositis pain), it might be compounded at a concentration for topical use (e.g., 5 mg/mL as a rinse) rather than systemic dosing

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