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The complete sequence is documented in published technical references [3]

M-YS and J-WK conducted the literature search and collected the data

It plays a crucial role in glucose homeostasis by: Enhancing insulin secretion from pancreatic beta cells in a glucose-dependent manner [8] [9] Suppressing glucagon release , thereby reducing hepatic glucose production Slowing gastric emptying , which moderates postprandial glucose excursions Promoting satiety through actions on appetite centres in the brain GLP-1 receptor agonists mimic these physiological effects but with extended half-lives, allowing for once-weekly or once-daily administration

Decreased availability of intestinal dopamine in transmural colitis may relate to inhibitory effects of interferon- upon L-DOPA uptake