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Injection site reactions including temporary redness, swelling, or itching occur occasionally

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F-AFE inhibited Lyn, Fyn, Syk phosphorylation, involved in FcR1 signaling, and phosphoinositide phospholipase C (PLC) 1/2 and protein kinase C (PKC) phosphorylation, associated with degranulation processes, as well as Extracellular Signal-Related Kinases (ERK) 1/2, JNK, p38, and Akt phosphorylation, associated with cytokine expression [83]

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