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found that using FA as a matrix for MALDI-MS analysis of oligonucleotidefluorophore conjugates significantly increased signal intensity, mass accuracy, and S/N ratio compared to the 3-HPA matrix

Separate-Vial Reconstitution Spec BAC water added BPC-157 (10 mg vial) 2.0 mL TB-500 (10 mg vial) 2.0 mL Spec Final concentration BPC-157 (10 mg vial) 5.0 mg/mL TB-500 (10 mg vial) 5.0 mg/mL Spec 10 units (0.10 mL) delivers BPC-157 (10 mg vial) 500 mcg TB-500 (10 mg vial) 500 mcg Spec 20 units (0.20 mL) delivers BPC-157 (10 mg vial) 1.0 mg TB-500 (10 mg vial) 1.0 mg Spec Doses per vial (typical) BPC-157 (10 mg vial) ~2040 days TB-500 (10 mg vial) ~45 loading doses This separate-vial row keeps the same 10 mg-per-compound assumption as the 20 mg pre-blend, but the compounds are reconstituted and drawn independently

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Peer review Peer review information Nature Reviews Cancer thanks Dong Gao and the other, anonymous, reviewer(s) for their contribution to the peer review of this work