And yes, GLP-1s have been associated with medullary thyroid cancer in rats but even some of the rats in those early studies that were taking the placebo (inactive medication) as part of the control group developed thyroid cancer
Oct 2011;25 Suppl B:22B-28B
Glucagon-like peptide-1 receptor agonists and the cardiovascular outcomes trials: effects on cardiovascular risk To establish the safety of a new antidiabetic therapy to treat T2D, the FDA required sponsors to demonstrate that the therapy did not result in an unacceptable increase in CV risk
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