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Natural DPP4 inhibitors: Research shows that several herbal supplements, including resveratrol, luteolin, and apigenin, inhibit DPP4

Study B, employing a crossover design, demonstrated that twice-daily PT-141 administration resulted in greater mean body weight reduction (1.7 kg) versus placebo (0.9 kg)

These approaches are based on the unusual observation that workers exposed to a chemical called 2,4-dinitrophenol (DNP), which was being used in French munitions factories, lost weight, felt fatigued, sweated excessively and exhibited elevated body temperature (hyperthermia)

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