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The takeaway from these studies: Obesity is a chronic condition and without ongoing treatment (whether medication, surgery, or intensive behavioral support), biology will try to pull weight back up

[ Disclaimer: This article is for informational purposes only and does not constitute medical advice

VESALIUS-CV Trial PCSK9 Inhibition in High-Risk Primary Prevention 12,257 high-risk patients (no prior MI/stroke) received evolocumab 140 mg q2w or placebo over 4.5 years

GLP-1 receptor agonist therapy requires ongoing assessment and potential dose adjustments based on treatment response, tolerability, and evolving clinical needs