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According to the MHRA-approved Summary of Product Characteristics (SmPC), headaches are reported by approximately 14.8% of patients taking Wegovy, compared to around 11.3% in placebo groups

However, in the CA1 hippocampal subregion the current is normally outward (344), and thus increased expression of 42 GABA receptors paradoxically results in ALLO attenuating rather than enhancing inhibition