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To find out, they looked at endoscopies and colonoscopies performed on 209 patients who were all overweight or obese (mean BMI of about 34) and averaging about 63 years of age

A clinical trial of sitagliptin in a small sample of patients with impaired glucose tolerance and mild T2DM found significant reductions in carotid intimal thickness in sitagliptin compared with diet control alone [122]

The first-line approach involves lifestyle and dietary modifications that reduce reflux triggers and accommodate the altered gastric emptying associated with these medications