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In the cumulative toxicity test, Kunming mice were injected with 500 mg kg 1 LAAM GSH-CQDs on days 0, 4, and 7, respectively, and the dose was increased to 1000 mg kg 1 on days 10 and 13, with an accumulated dose of 3500 mg kg 1

Results suggest it may influence gene expression that helps control abnormal growth, though this research is still early and exploratory

Apremilast (Otezla) is an oral anti-inflammatory drug that is approved by the Food and Drug Administration (FDA) for plaque psoriasis and psoriatic arthritis (FDA 2014

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