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Objective markers (IGF-1, metabolic panels, and where tested, biological age) typically show measurable improvement

The very low rate constants for direct, glutathione-independent dithiol-disulfide exchange reactions between glutaredoxins and roGFP2 or other protein(S 2 )/protein(SH) 2 couples (despite favorable thermodynamics) are a prerequisite and great advantage for reliable redox measurements in vivo

[233] also developed and demonstrated biological micromotors prepared from microorganisms (acidophilic microalgae that can survive in extreme environments) and verified their tolerance under the low pH conditions in the human stomach

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