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Injecting as close as anatomically safe to the target tissue maximises local tissue concentration

This is sometimes referred to as a methyl trap, where folate becomes functionally unavailable without sufficient B12, and vice versa

Studies show the consuming an excessive amount of vitamin B12 may: Increase the risk of cardiovascular events in people with diabetic nephropathy : A study published in JAMA sought to determine whether B vitamin therapy was able to slow the progression of diabetic nephropathy (kidney damage due to diabetes) and prevent vascular complications

Dosage How much Vitamin B12 + Minerals injection should be given to horses