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Plasma DPP-4 activity, active GLP-1, body weight, and plasma TG after a 5-hour fast ( A , C , E , and G ) and plasma TG, AUC over 180 minutes, and plasma levels of active GLP-1 before and 10 minutes after oral gavage of olive oil ( B , D , F , and H ) during a lipid tolerance test (LTT) in 16- to 19-week-old Dpp4 / vs

Phase 2 saw -24.2% at 48 weeks at 12 mg, but individual results varied widely

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