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Intracellular Glu is produced from glutamine (Gln) catalyzed by glutaminase (GLS, with two different isomers GLS1 and GLS2) [29, 30]

The mice were euthanized through CO2 inhalation when the tumor volume surpassed 1500 mm or when the mice showed signs of serious weight loss, dreadful weakness, or Unhealed ulcers, indicating they were moribund

LYNAE L-cysteine, one of the principal ingredients helps prevent excessive melanin from being generated

The PNMT gene is located on chromosome 17q12 and is composed of 4 exons that generate two alternatively spliced mRNAs, one of which is non-coding, the other encodes the functional protein of 282 amino acids