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This also explains why effects can outlast blood levels

However, an elevation of B12 in ones serum can be tied to the MTHFR gene variation , as those with the MTHFR gene variation may be unable to properly use non-methylated B12

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Biochemical determination of antioxidant enzymes Glutathione peroxidase (GPx, EC 1.11.1.9) activity was determined using BioVision tests (BioVision, Mountain View, CA, USA)