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In vivo, ouabain-treated mice harbored a decrease of senescent cells in an OIS model, a whole-body irradiation model as well as in aged mice

Cognitive, Affective, and Behavioral Neuroscience, 24, 617-630

Further, other studies stated that neurodegeneration in patients with T2DM could be considerably lowered by targeting cytokines, cytokine receptors, and nuclear transcription factors linked to inflammation, like IL-6 and TNF- , alone or in combination [48]