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We focused on the metabolism of sulfur compounds, which are greatly involved in the redox action in the body, and conducted a comprehensive analysis of 87 types of sulfur metabolites (sulfur index analysis) in a total of four groups: the Con-DSS group, the Si-DSS group, the control group, and Si groups

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In addition to these conventional sites of mitochondrial ROS generation, it has been recently reported that the branched-chain 2-oxoacid dehydrogenase (BCKDH) complex in mitochondria can produce superoxide and H 2 O 2 at higher rates than complex I from mitochondria (Quinlan et al., 2014)

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