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Its primary function is to protect the skin from oxidative damage caused by factors like UV rays, pollution, and aging

This begs the question as to whether there may be a tendency for MTHFR activity, and hence methylation and thymidylate pathways to be modulated by a changing UV environment

Cytokines and growth factors in endometrial tissue provide essential paracrine and autocrine signals that regulate receptivity and support embryonic development [345]