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Burgos, E

Mol Psychiatry , 2017, 22: 328335 Yang WS, SriRamaratnam R, Welsch ME, Shimada K, Skouta R, Viswanathan VS, Cheah JH, Clemons PA, Shamji AF, Clish CB, Brown LM, Girotti AW, Cornish VW, Schreiber SL, Stockwell BR

Because this dependence means the body will crave more drugs to abate withdrawal, a longer history of abuse tends to make withdrawal symptoms more severe and drawn out