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Further kinetic analyses showed that Wt MhTyrA p had a K m of 378 M and turnover rate ( k cat ) of 2.4 s 1 using prephenate substrate and NADP + cofactor (Figure 4, Table 1), which are comparable to previously characterized microbial TyrA p enzymes (Bonvin et al., 2006
If negative vitamin B12 supplement side effects persist, consider decreasing your dosage, or consult with your doctor
It has not undergone Phase I, II, or III human clinical trials and is not recognized as Generally Recognized as Safe (GRAS)
Additional information on materials and methods can be found in the Supplementary Materials and Methods
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