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Impact of obesity as an independent risk factor for the development of renal injury: implications from rat models of obesity

Given that aging is associated with a decline of mitochondrial functions along with the development of aging-related diseases, and given that the tissue and circulating levels of MOTS-c fall with age, it is compelling to hypothesize that declining MDP levels are also related to age-related metabolic deterioration

Briefly, on day 0, iPSCs were dissociated with TrypLE Select (GIBCO, Thermo Fisher Scientific, MA, USA) and disseminated on a mixed coating of poly-l-lysine (final 0.0002% v/w, Merck, Darmstadt, Germany), and Matrigel (final 2% v/v, Corning, NY, USA)

J Zhejiang Univ B (2022) 23:17388