The addition of ionomycin to iRPMI alone induced a rapid and significant increase of PS exposure after only 1 h incubation (T 1h =0.1% in DMSO vs
We and others previously demonstrated GDF8 and ActA are the two major ligands which mediate the muscle minimization actions of the ActRIIA/B receptors in non-obese mice and NHPs 22,28,30 , and we have further shown that dual blockade of GDF8 and ActA led to much larger increases in muscle mass than blocking either ligand individually, and that dual blockade matched the muscle growth actions of broader ActRIIA/B blockade 28 , similar to effects seen when using a dominant-negative type II receptor or pro-domains of GDF8 and activins 22,26,27
24th February 2025, A/Prof Chee L Khoo This is one of the most common questions asked at glucagon-like peptide 1 receptor agonist (GLP1-RA) CPD meetings
Misconception 4: "I missed the news cycle, so I missed my chance." The statute of limitations, not the media cycle, determines your window