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The use of GLP-1 agonists compared with bupropion-naltrexone was associated with increased risk of pancreatitis, bowel obstruction, and gastroparesis (a condition that slows or prevents the stomach from emptying its contents into the small intestine), but not biliary disease.8 Nutraceutical Compensation There are some nutraceuticals which may help compensate for some of the adverse effects associated with the use of GLP-1 agonist drugs

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