#Obesity #Type2Diabetes #GLP1 #ClinicalTrials #Phase3 #Biotech #Pharma #DrugDevelopment #HealthcareInnovation #LifeSciences #MetabolicHealth #PharmaceuticalIndustry Kaiera Hengrui Reports Positive GLP-1 Therapy Results Promising Progress in the Obesity & Type 2 Diabetes Space Kaiera and Hengrui have reported positive Phase 3 results for their investigational oral GLP-1 therapy, marking another significant step forward in the evolving landscape of metabolic disease treatment
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Some subjects experience declining response a Phase 2 trial found IGF-1 levels plateaued at month 6 despite continued daily MK-677 dosing, suggesting partial desensitization of the GH-IGF-1 axis under constant stimulation
AC has received consulting or speaker fees from Bristol Meyer Squibb, AstraZeneca, Boehringer Ingelheim, Eli Lilly, Merck Sharp & Dohme, Novartis, Novo-Nordisk, Sanofi-Aventis, Sigma-Tau, Takeda