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Based on current trial populations and how the FDA has handled semaglutide and tirzepatide approvals, expected eligibility criteria are: BMI 30 , or BMI 27 with at least one weight-related condition (type 2 diabetes, hypertension, dyslipidemia, OSA) Adults 18 and older Not pregnant or breastfeeding No history of MTC or MEN 2 Retatrutide will almost certainly launch at a high price point estimates suggest $1,200$1,500 per month at list price

Diabetes is a chronic illness that develops when the pancreas either produces insufficient amounts of insulin or when the body cannot properly utilize the insulin that it does

The combination of GLP-1R-mediated appetite suppression, GIPR-mediated adipose tissue metabolism, and GCGR-driven energy expenditure makes it one of the most comprehensive research tools for studying multi-pathway obesity biology in a single compound

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