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doi: 10.1038/s42255-023-00783-1 89 MoriyamaM.KoshibaT.IchinoheT

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Wound healing: accelerated closure in rodent excision models Collagen synthesis: type I and III collagen upregulation in fibroblast cultures Hair biology: follicle enlargement observed in organ culture models Anti-fibrotic: decorin upregulation may limit scar tissue formation Antioxidant defense: SOD and catalase gene upregulation via copper-dependent pathways Evidence Base & Study Quality A critical distinction between these two peptides is the breadth of their evidence base