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Further, unlike GLP-1, GIP increases triglyceride storage in white adipose tissue, does not delay gastric emptying, and may impact bone remodeling--functions that were thought to limit GIPs utility in T2D and weight loss

Provided the physiological basis for the clinical practice of administering GH secretagogues in a fasted state to optimize the GH response, and for bedtime dosing protocols that align with the natural nocturnal GH peak that occurs during slow-wave sleep