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Funding This work is supported by NIH R01DK121995, NIH R01DK107282, and by an American Diabetes Association grant (119-IBS-252) to DAS and institutional NIH Training grant NIH T32DK120521 to MB

[10] It has a black box warning for pregnancy in the United States

doi:10.1002/osp4.342 42

The rax1-1 mutant is characterized by an enhanced APX2 gene expression due to a lesion in the gene encoding GSH1 concomitantly with a 50% reduced GSH content