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The mitochondrial dysfunction induced by iron overload in cardiac tissue is a significant contributor to IOC [17]

Contrast dye procedures If you need a CT scan or other imaging procedure with iodinated contrast dye, your prescriber will typically hold metformin for 48 hours before and after the procedure

This imbalance impairs vasodilation, promotes vasoconstriction, and increases vascular permeability, creating a conducive environment for the infiltration of lipoproteins and immune cells into the arterial wall

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