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Mitochondrial dysfunction in Kupffer cells plays a central role: IR causes Kupffer cell mitochondria to release mtDNA and ROS, activating NLRP3 inflammasomes which then release IL-1 that amplifies neutrophil recruitment (67)
Although telogen effluvium is extremely distressing, for the majority of people it is temporary and resolves on its own within three to six months after the onset of hair loss, adds Dr
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