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Finally, animal-to-human translational limitations are significant: germ-free mouse models and CUMS paradigms involve physiological conditions that do not faithfully recapitulate human psychiatric or functional gastrointestinal disorders, and microbiota transplant experiments in rodents cannot be directly extrapolated to clinical practice

Mounjaro (tirzepatide) is manufactured by Eli Lilly and received FDA approval in 2022 for type 2 diabetes in adults and children aged 10 and older

Cancer cachexia: developing multimodal therapy for a multidimensional problem

BRET signal was calculated as the ratio of the 535/30 nm emission over the 475/30 nm emission