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Sampling brain metastases Historically, prognostic models for BM, such as recursive partitioning analysis (RPA) [33] and Graded Prognostic Assessment (GPA) [34], have incorporated tumor histology as a factor, typically based on biopsy of the primary tumor

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If you plan to become pregnant, talk to your cardiologist, obstetrician and primary care provider (PCP) well in advance

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