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Peer review Peer review information Nature Reviews Nephrology thanks Mark Cooper, Francesco Giorgino and the other, anonymous, reviewer(s) for their contribution to the peer review of this work

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GLP-1R agonists were developed as long-acting therapeutic agents to overcome the short half-life of endogenous GLP-1, namely Semaglutide (Ozempic, Wegovy, Rybelsus)

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Patients typically lost 18-20% of their body weight over one year 34 , helping reduce airway obstruction

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Symptoms and clinical follow-up remain essential

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