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However, some clinics offering the retatrutide-cagrilintide combination use a ratio of approximately 5:1 (retatrutide to cagrilintide), which at a retatrutide dose of 10-12 mg would put cagrilintide at 2.0-2.5 mg

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The implication for clinical practice is that restoring youthful MOTS-c signaling might be a mechanistically legitimate target for longevity intervention