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Single cell spatial transcriptomics can inform cell-to-phenotype over time mapping by capturing the physical tissue structure, which is of special importance for tissues like the brain (Khodosevich and Sellgren, 2023

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Additionally, melatonin secretion patterns in NS workers were associated with differential methylation of key circadian genes, including RORA, MTNR1A, and PER3, suggesting a potential link between circadian disruption, epigenetic regulation, and cancer risk 196