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Some studies have reported that depression caused by chronic stress disrupts the BDNFtropomyosin related kinase B (TrkB) receptor signaling pathway in the PFC and hippocampus, and ultimately contributes to impaired synaptic maturation, synaptic protein synthesis, and glutamate receptor cycling (Hoeffer and Klann, 2010

This data may or may not perfectly match the specific formulation, concentration, or packaging used by that pharmacy

Circulation2008 May 6;117(18):2340-50

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