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It often leads to sarcopenic obesity, where muscle is lost and fat accumulates, which can reduce function and potentially affect long-term outcomes

BOX 7-1 Lesion Characteristics in Nails That Should Raise a Red Flag Location: Single digit, thumb, or great toe nails Appearance: Fast growth, longitudinal melanonychia, band width more than 3-5 mm Hutchinsons Sign: Periungual pigmentation of skin Nail Dystrophy: Notch in free distal nail margin, surface irregularity, oozing, or bleeding lesion similar to ingrown nail Melanonychia striata Brown longitudinal stria (plural is striae) that occurs in the nail is called melanonychia striata

The final dose your doctor prescribes depends on your individual metabolic needs, weight loss goals, and how well you tolerate the medication at each level

This article describes the role of 3,5-diiodothyronine in reducing hepatic fat