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It also enhances BDNF expression and reduces neuroinflammation, supporting cognitive recovery and mental clarity during waking hours

Preclinical studies indicate that NNMT knockdown or inhibition can protect against diet-induced weight gain and improve metabolic parameters without reducing food intake [5] [6]

Open field test The open field test was performed for assessing psychomotor results and exploratory behaviour in a 45 cm 45 cm 40 cm black acrylic box arranged into twenty-five squares, as reported previously (Reference Tasdemir and Colak18)