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The greatest effects were observed with weekly tirzepatide 15 mg, which led to 17.8% to 20.9% weight loss at 72 weeks

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However, the clinical benefit of this modality has still been limited due to several defects such as adverse events, acquired drug resistance, tumor recurrence, and lack of validated biomarkers, which impel further research on mechanisms of tumor angiogenesis, the development of multiple drugs and the combination therapy to figure out how to improve the therapeutic efficacy

Assessing the economic burden of Alzheimer's disease patients first diagnosed by specialists