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Albumin production and maintenance of morphologic features were assessed as these are common markers used to evaluate hepatic phenotype in vitro ( Cell Viability Assay Optimization Three viability assays were trialed during model development: calcein AM, 3-(4,5-dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide (MTT), and neutral red

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CD47 targeting enhanced macrophage-mediated phagocytosis, while PD-L1 and EGFR conjugates led to sustained receptor downregulation and reduced cell migration, respectively, without causing toxicity even at higher doses