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For an early-stage acquisition where the targets asset has not yet reached Phase III, an earn-out can defer 40-60% of the total consideration to milestones including Phase III initiation, Phase III readout, NDA submission, approval, and first-year revenue thresholds

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In the STEP1 trial, semaglutide (2.4 mg) induced a mean weight loss of 14.9% among overweight or obese patients who did not have T2DM [68]

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Age-dependent shift in macrophage polarisation causes inflammation-mediated degeneration of enteric nervous system

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