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The program established a favorable safety profile but the Phase IIb endpoint did not differentiate sufficiently from placebo to support continued development for obesity

Novo CEO Mike Doudstar told CNBC in mid-February that 246,000 patients were taking oral Wegovy

You'll start on a low dose so your body has time to adjust, and the dose increases gradually over the first 16 weeks. The standard schedule is 0.25mg once a week for the first four weeks, then 0.5mg, then 1mg, then 1.7mg, and finally 2.4mg as your ongoing maintenance dose from week 17 onwards. Each step lasts around four weeks. Your clinician may slow this down if you're struggling with side effects, or keep you on a lower dose if it's working well for you

Vegans and vegetarians may require supplementation, as plant-based foods contain negligible B12 unless fortified