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Trends Endocrinol Metab 2019;30:701-9.ArticlePubMed 104

GLP-1 mediates the insulinotropic and glucose-lowering effects of T3 We also found that GLP-1 treatment could elevate insulin levels, decrease glucose levels, and improve oral glucose tolerance in MMI mice (Fig

Originally proposed in 1976 as a new treatment for Crigler-Najjar syndrome type 1 and validated in hyperbilirubinemic Gunn rat models, HTx has undergone substantial advances over time (Matas et al., 1976)

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