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& Barber, R

For AST, the analysis showed a statistically significant decrease (MD = 4.82

Should any unusual symptoms appear, discontinue use immediately and seek medical advice.

A 2019 meta-analysis in European Journal of Endocrinology found that each 10% reduction in body weight was associated with a 2-3 nmol/L increase in total testosterone, placing the weight loss achieved with tirzepatide well within the range needed for clinically meaningful hormonal improvement (Corona et al., 2019, European Journal of Endocrinology )