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Finally, given that clinician-driven dose changes were allowed for participants on both IR-Tac and LCPT, some participants may not have been at steady state on day 7 or 14, which may have underestimated t 1/2eff

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This regulation of the actin cytoskeleton governs cell migration: cells need to polymerize and depolymerize their actin to crawl, divide, and close wounds