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Final Statewide Average Default Cost-to-Charge Ratios (CCRs) In addition to using CCRs to estimate costs from charges on claims for ratesetting, we use overall hospital-specific CCRs calculated from the hospital's most recent cost report (OMB control number: 0938-0050 for Form CMS-2552-10) to determine outlier payments, payments for pass-through devices, and monthly interim transitional corridor payments under the OPPS during the PPS year

In the draft policy, the FDA stated that NAC is not considered a dietary supplement in the United States because it was approved as a new drug in 1963, well before it was marketed as a dietary supplement