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HS-GC/MS analysis was performed using a GCMS-QP2010 system (Shimadzu, Kyoto, Japan) with an AOC-5000 auto-injector (Shimadzu, Kyoto, Japan) with an AQUATIC capillary column (internal diameter 60 m 0.25 mm

The Limitations of Traditional Melasma Treatments Conventional approaches to treating melasma have included: Topical agents (hydroquinone, retinoids, corticosteroids) Chemical peels Conventional laser therapies Oral medications Lifestyle modifications Sun protection measures While these methods can offer some improvement, they often fall short of delivering comprehensive, long-lasting results