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Researchers compared outcomes with users of another weight loss drug, bupropion-naltrexone (n = 654), and monitored all patients for development of biliary disease, pancreatitis, bowel obstruction or gastroparesis

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Bone remodeling takes time, so stay consistent for at least 8 to 12 weeks

Both work through different pain-relief pathways and do not directly interfere with GLP-1 receptor signaling